Two men have died after their car, Renault Megane was involved in an accident on Bolton Road in Pendlebury with a Mitsubishi Shogun
One is believed to be in their 30s and the other in their 40s.
The driver of the Mitsubishi– a man in his 60s – was taken to hospital with serious injuries. He remains there in a stable condition.
Emergency services remain at the scene whilst investigation work is carried out. The road remains closed.
Enquiries are ongoing and no arrests have been made.
PC Karl Horner of GMP’s Serious Collision Investigation Unit said: “This is an absolutely tragic incident, in which two people have very sadly lost their lives. Our thoughts are with their families at this unimaginably distressing and difficult time. Our thoughts also remain with the man who is receiving treatment in hospital – we hope he makes a recovery as soon as is possible. We have specially trained officers supporting those family members who have been affected.
“The investigation will be led by GMP’s Serious Investigation Unit, who specialise in investigating devastating incidents like this one. We hope that we can provide a measure of comfort to the distraught family members, by meticulously investigating the circumstances that led to two people losing their lives this morning.
“I would appeal directly to anyone who saw either vehicle in the lead up to the incident – do you have dash cam footage or any information that could assist us? I would urge you to get in touch as soon as possible, so we can further progress our investigation.”