Two people have been killed in an eight vehicles pile up on the M40 this morning between J5 and J4 southbound.
A woman in her sixties and a man in his seventies, died at the scene say Thames Valley Police.
A further two people sustained serious injuries and were taken to hospital where they remain.
10 people sustained minor injuries, a number of who were taken to hospital for additional checks.
Detective Chief Inspector Mike Bettington, of the Joint Operations Roads Policing Unit, said: “Our thoughts remain with the family and friends of the two people who died.
“We are appealing to anyone who may have witnessed the collision, or who may have dash-cam footage, to please get in touch.
